First in the series set in the fledging university of Cambridge. Matthew Bartholomew is a doctor and teacher in the University at the time of the plague. There have been a series of unsettling deaths in the University recenrtly, culminating in the supposed suicide of the master of Michaelhouse college and the murder of three of its fellows. Bartholomew sets out to find out what's happened, in the midst of trying to cure the plague, which has also descended on the town. He's not the most talented detective in literature, and that, in part, is it's charm. He's just trying to spot things and string facts together. It all gets a bit complicated, but not so difficult to follow - although you do finish wondering if anyone could have got to the bottom of it all earlier.